Downstream Processing Market to Reach USD 22.03 Billion

Author : BloggerDJ
Publish Date : 2021-04-22

Downstream Processing Market to Reach USD 22.03 Billion

This report aims to provide detailed insights into the global downstream processing market. It provides valuable information on the type, procedure, application, and region in the market. Furthermore, the information for these segments, by region, is also presented in this report. Leading players in the market are profiled to study their product offerings and understand the strategies undertaken by them to be competitive in this market.

Key Factors Driving Market Growth:

The growth in the Downstream Processing Market will majorly be driven by the increasing demand for biopharmaceuticals, as downstream processing steps play a significant role in providing pure and quality products. However, the high cost of instruments used in downstream processing is expected to restrain the growth of this market. On the other hand, patent expiration of blockbuster biopharmaceutical products represents significant growth opportunities for the key players in the Downstream Processing Industry.

Revenue Growth Analysis:

The global downstream processing market is poised to reach USD 22.03 Billion by 2021 from USD 10.32 Billion in 2016, at a CAGR of 16.4% from 2016 to 2021.

Browse 68 market data Tables and 40 Figures spread through 139 Pages and in-depth TOC on "Downstream Processing Market"

The global Downstream Processing Market is broadly segmented on the basis of technique, product, application, end user, and region. On the basis of technique, the market is segmented into purification, solid-liquid separation, and clarification/concentration.

In 2016, the purification segment accounted for the largest share of the market. This largest share and the high growth is attributed to the need for highly pure biopharmaceutical products to meet the regulatory standards, as downstream purification plays a significant role in enhancing the purity and quality of products aiding the growth of the purification market.

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On the basis of product, the market is broadly classified into chromatography columns and resins, filters, membrane adsorbers, single-use products, and other products (consumables and accessories). In 2016, the chromatography columns and resins segment accounted for the largest share of the Downstream Processing Market.

Columns and resins are the most important component of a chromatography system and are extensively used in the separation, recovery, and purification of components of a bioactive sample. The constant need for newer and different types of columns and resins is likely to fuel market growth.

North America (comprising the U.S. and Canada) is expected to account for the largest share of the global Downstream Processing Market in 2016, followed by Europe. North America is the world's largest pharmaceutical market and a leader in biopharmaceutical research. Rising quality requirements have emphasized the need for advanced bioproduction technology in this region. Asia-Pacific is expected to grow at the highest CAGR during the forecast period. The Asia-Pacific Downstream Processing Market, particularly in China, Japan, India, and South Korea, is expected to witness high growth. In addition, growth in these markets will be fueled by significant investments by key market players, increasing government support, developing R&D infrastructure, and growing expertise & academic excellence.

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The Downstream Processing Market is dominated by established players such as Thermo Fisher Scientific Inc. (U.S.), GE Healthcare (U.S.), Sartorius Stedim Biotech S.A. (France), Merck Millipore (Germany), and Danaher Corporation (U.S.).

Merck Millipore (Germany) held the top position in 2015. The company has strengthened its position in the market through the adoption of organic as well as inorganic strategies such as product launches and acquisitions. Between 2014 and 2016, the company introduced various new products in its portfolio. For instance, in April 2016, Merck Millipore launched the Mobius 1000L single-use bioreactor that delivers enhanced efficiency and ease-of-use for biopharmaceutical manufacturing workflows. However, In November 2015, Merck acquired Sigma-Aldrich (U.S.).

This research report categorizes the market on the basis of technique, product, application, end user, and region.

Global Downstream processing Market, by Technique

  • Purification
  • Solid-liquid Separation
  • Clarification/Concentration

Global Downstream processing Market, by Product

  • Chromatography Columns and Resins
  • Filters
  • Membrane Adsorbers
  • Single-use Products
  • Other Products (Consumables and Accessories)

Global Downstream processing Market, by Application

  • Monoclonal Antibody Production
  • Vaccine Production
  • Insulin Production
  • Immunoglobulin Production
  • Erythropoietin Production
  • Other Applications (Interferons, Fusion Proteins, Growth Hormones, Blood Coagulation Factors, Anticoagulants, Medical Enzymes, Anti-bacterial (Antibiotics), and Colony Stimulating Factors)

Global Downstream processing Market, by End User

  • Biopharmaceutical Manufacturers
  • Contract Manufacturing Organizations (CMOs)

Global Downstream processing Market, by Region

  • North America
    • U.S.
    • Canada
  • Europe
  • Asia-Pacific
  • Rest of the World (RoW)

Available Customizations

With the given market data, MarketsandMarkets offers customizations as per the company’s specific needs. The following customization options are available for the report:

Geographical Analysis

  • Further breakdown of the APAC downstream processing market into China, Japan, India, and Rest of Asia-Pacific
  • Further breakdown of the European market into Germany, France, the U.K., and Rest of Europe

Company Information

  • Detailed analysis and profiling of additional market players (Up to 5)


  • Vendors/service providers
  • Research and consulting firms
  • Biopharmaceutical manufacturers
  • Contract manufacturing organizations (CMOs)
  • Contract research organizations (CROs)

To know about the assumptions considered for the study, download the pdf brochure

Scope of the Report

  • The market study doesn’t cover the market size in terms of volume
  • Some companies in this market are privately owned and their revenues are not available in the public domain. Hence, revenue for those companies are not included in this report
  • Company developments not reported in the public domain are not included in this report

Premium Insights (Page No. - 28)
    4.1 Downstream Processing Market Snapshot, 2016 vs 2021
    4.2 Market, By Product and Region
    4.3 Downstream Processing Market, By Technique, 2016 vs 2021 (USD Billion)
    4.4 Market, By Application, 2016 vs 2021 (USD Billion)
    4.5 Market, By End User, 2016 vs 2021 (USD Billion)
    4.6 Downstream Processing Market, By Region

5 Market Overview (Page No. - 32)
    5.1 Introduction
           5.1.1 Drivers
           Increasing Demand for Biopharmaceuticals
           Increasing R&D Expenditure in Biopharmaceutical Companies
           5.1.2 Restraints
           High Cost of Instruments
           5.1.3 Opportunities
           Patent Expiry
           5.1.4 Challenges
           Purification Bottleneck
           Lack of Single-Use Options
           Dearth of Skilled Professionals

6 Downstream Processing Market, By Technique (Page No. - 38)
    6.1 Introduction
    6.2 Purification Techniques
           6.2.1 Gel Chromatography
           6.2.2 Ion Exchange Chromatography
           6.2.3 Affinity Chromatography
           6.2.4 Hydrophobic Interaction Chromatography
    6.3 Solid-Liquid Separation
           6.3.1 Filtration
           Tangential Flow Filtration
           Normal Flow Filtration
           6.3.2 Centrifugation
    6.4 Clarification/Concentration

7 Downstream Processing Market, By Product (Page No. - 47)
    7.1 Introduction
    7.2 Chromatography Columns and Resins
    7.3 Filters
    7.4 Membrane Adsorbers
    7.5 Single-Use Products
    7.6 Other Products

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